amide - meaning and definition. What is amide
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What (who) is amide - definition

ANY DERIVATIVE OF AN OXOACID IN WHICH AN ACIDIC HYDROXY GROUP HAS BEEN REPLACED BY AN AMINO OR SUBSTITUTED AMINO GROUP
Carboxamide; Amides; Amide group; Amidation; Bodroux reaction; Amido; Amide bond; Leuckert amide synthesis; Acid amide; Primary amide; Secondary amide; Tertiary amide
  • Mechanism for acid-mediated hydrolysis of an amide.<ref>{{March6th}}</ref>
  • General structure of an amide (specifically, a carboxamide)
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  • [[Asparagine]] ([[zwitterionic]] form), an [[amino acid]] with a side chain (highlighted) containing an amide group
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  • Chapman Rearrangement
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  • [[Formamide]], the simplest amide
  • π molecular orbitals]] (gray).

Amide         
·noun A compound formed by the union of amidogen with an acid element or radical. It may also be regarded as ammonia in which one or more hydrogen atoms have been replaced by an acid atom or radical.
amide         
['e?m??d, 'am??d]
¦ noun Chemistry
1. an organic compound containing the group ?C(O)NH2.
2. a salt-like compound containing the anion NH2-.
Origin
C19: from ammonia + -ide.
Amide         
In organic chemistry, an amide ( or or , also known as an organic amide or a carboxamide, is a compound with the general formula RC(=O)NR′R″, where R, R', and R″ represent organic groups or hydrogen atoms. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine.

Wikipedia

Amide

In organic chemistry, an amide, also known as an organic amide or a carboxamide, is a compound with the general formula R−C(=O)−NR′R″, where R, R', and R″ represent any group, typically organyl groups or hydrogen atoms. The amide group is called a peptide bond when it is part of the main chain of a protein, and an isopeptide bond when it occurs in a side chain, such as in the amino acids asparagine and glutamine. It can be viewed as a derivative of a carboxylic acid (R−C(=O)−OH) with the hydroxyl group (−OH) replaced by an amine group (−NR′R″); or, equivalently, an acyl (alkanoyl) group (R−C(=O)−) joined to an amine group.

Common examples of amides are formamide (H−C(=O)−NH2), acetamide (H3C−C(=O)−NH2), benzamide (C6H5−C(=O)−NH2), and dimethylformamide (H−C(=O)−N(−CH3)2). Some uncommon examples of amides are N-chloroacetamide (H3C−C(=O)−NH−Cl) and chloroformamide (Cl−C(=O)−NH2).

Amides are qualified as primary, secondary, and tertiary according to whether the amine subgroup has the form −NH2, −NHR, or −NRR', where R and R' are groups other than hydrogen.

The core −C(=O)−(N) of amides is called the amide group (specifically, carboxamide group).

Amides are pervasive in nature and technology. Proteins and important plastics like Nylons, Aramid, Twaron, and Kevlar are polymers whose units are connected by amide groups (polyamides); these linkages are easily formed, confer structural rigidity, and resist hydrolysis. Amides include many other important biological compounds, as well as many drugs like paracetamol, penicillin and LSD. Low-molecular-weight amides, such as dimethylformamide, are common solvents.

Examples of use of amide
1. Actavis, where Mr Bjorgolfsson is the chairman and biggest shareholder, has expanded into G7ermany, Eastern Europe, Scandinavia and Russia and is in the process of buying Amide, a US drug maker, for at least $500m.
2. Basically, he replaced an amide link (between amine and acid) with an ester link (between alcohol and acid). After he rebuilt the molecule, the resulting substance – which he calls Oligo X – was a raw material with properties similar to those of polyester, but which could be broken down like an organic substance.